Archive of Clinical Cases

Cancer cervical cells

Conținutul

Department of Ophthalmology, Grigore T.

Case Report

E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.

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The method used for the detection of HPV was real time polymerase chain reaction. The evolution cancer cervical cells favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence.

The biologic behavior of cancer cervical cells cervical carcinoma after neoadjuvant therapy NAT according to immunohistochemical expression of E-cadherin and CD44v6 Mihaela Madalina Gavrilescu, Raluca Balan, Viorel Scripcariu, Dan Ferariu, Ludmila Lozneanu, Diana Popovici, Cornelia Amalinei Abstract The efficiency of neoadjuvant therapy in cervical carcinoma has been well demonstrated, although the cellular mechanisms of different response to this treatment have not been thoroughly investigated. The aim of our study was to assess the correlations between the alterations in E-cadherin and CD44v6 immunoexpression in cervical carcinoma, as a tool of evaluation the response to neoadjuvant therapy and its prognostic cancer cervical cells.

Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, cancer cervical cells, anushead and neck cancers oral cancer cervical cells, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.

The association cancer cervical cells HPV infection and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.

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Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half. He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist.

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The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses. All other ophthalmological findings were normal. Conjunctival culture was performed before surgery, and no bacterial infection was found.

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The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes. Cancer cervical cells limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done.

At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing. Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.