Dramatic Growth In Cancer Rates Among US Elderly, Minorities Predicted

Aggressive cancer research

Conținutul

    Despite advances in understanding the molecular biology of glioblastoma aggressive cancer research, WHO grade IV, these aggressive tumors are still incurable.

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    These statistics emphasize the need to develop new effective therapeutic strategies against this disease. The presence of cancer stem cells in brain tumors has been suggested in the recent years, extrapolating from other types of malignancies. The Notch signaling is a important pathway for survival of cancer stem cells.

    In light of recent molecular treatment resistance or inefficacy, the concomitant inhibition of Notch pathway and angiogenesis proposed in the present project could offer a promising strategy to surpass the cross talk between various pathways and to emerge as alternative therapies.

    Aggressive cancer research main objective of the present project is Evaluation of synergic effects of multiple signaling pathway inhibition cancer stem cell signaling — Notch, angiogenesis, PI3K signaling as potential novel therapeutical approaches for glioblastoma treatment. Project Objectives: The main objective of the present project is Evaluation of synergic effects of multiple signaling pathway inhibition cancer stem cell signaling — Notch, angiogenesis, PI3K signaling as potential novel therapeutical approaches for glioblastoma treatment.

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    Two papers published aggressive cancer research prestigious ISI journals. Two communications at renowned scientific congresses.

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