Skin cancer benign vs malignant,
The head and neck malignant tumor pathology can be addressed by multiple medical specialists: maxillofacial surgeons, dermatologists and plastic surgeons. Although considered skin cancer benign vs malignant less aggressive type of malignancy, the basal-cell carcinoma can extend to profound regions and require extensive surgery and immediate reconstructions of the defect area with regional or distant flaps.
Keywords basal-cell carcinoma, surgical extirpation, relapse, local flap Rezumat Tegumentul skin cancer benign vs malignant fi afectat de tumori maligne, cu preponderenţă carcinomul bazocelular, urmat de cel spinocelular şi melanomul malign. Patologia tumorală malignă din zona capului şi a gâtului se află la graniţa dintre multiple specialităţi: chirurgie maxilo-facială, dermatologie, chirurgie plastică. Deşi considerat o formă mai puţin agresivă local, carcinomul bazocelular poate avea cancerul uterin se transmite evoluţie locoregională infiltrativă în părţile profunde, implicând rezecţii largi şi reconstrucţie imediată cu lambouri locoregionale sau de la distanţă.
Cuvinte cheie carcinom bazocelular extirpare extinsă recidivă lambou local Introduction Skin cancer is the most frequent malignancy worldwide.
Между нашими двумя культурами простирается пропасть столь же бездонная, как и та, что некогда разделяла Землю и ее древние инопланетные колонии.
- Wart on foot reflexology
Он четко и без излишней драматизации изложил свою историю.
The most encountered histological subtypes are basal-cell carcinoma and squamous cell skin cancer benign vs malignant. Only inin USA, up to 5 million patients received treatment for these two types of cancer 1. Australia has the highest number of new cases of skin cancer in the world 2due to climate extensive sun exposure ; the vast majority of skin malignant tumours are UV radiation dependent.
From the histological perspective, the most encountered is basal-cell carcinoma, followed by squamous cell carcinoma.
Urmărirea pacienţilor cu carcinom bazocelular
The management of skin malignancies is divided into two major branches: surgery radical tumor resection, Mohs surgery, electrodessicationand conservative treatment photodynamic therapy, radiotherapy, cryotherapy and topical agents. Surgical treatment is the first intended treatment when dealing with skin cancer, and the excision should be tailored to ensure proper free margin around the tumor, of at least 6 mm.
If the lesion is found to be generated from the skin cancer benign skin cancer benign vs malignant malignant layer, the lymph nodes should also be investigated. The relapse or lymph metastasis risk is associated with the characteristics of the tumour: histological subtype, size, profound invasion, localization, and also the general condition of the patients immunosuppression, severe associated diseases.
The tumors skin cancer benign vs malignant href="http://kd-group.ro/papillomavirus-wratten.php">papillomavirus wratten with a high risk of relapse or metastases have poor differentiated morphology, have more than 2 cm in size, and are situated in the eye or in perioral region 4.
Follow-up in advanced basal-cell carcinoma
Case presentations Case I An year-old male patient was admitted to our department for a skin skin cancer benign vs malignant benign vs malignant region tumor developed approximately six months ago Figure 1. The patient had a medical history in our records: 12 years ago he received a right orbital exenteration for an advanced basal-cell carcinoma. The biopsy confirmed a secondary basal-cell carcinoma. A surgical plan was established: wide surgical excision and immediate reconstruction of the defect with advanced horizontal frontal flap Figure 1.
The healing went uneventful, and the histological examination confirmed the basal-cell carcinoma. The importance of the case lies in the development of a second basal-cell carcinoma, on the same side, 12 years after the primary tumor.
Figure 1. Frontal basal-cell carcinoma 12 years after exenteration Figure 1.
Upper left: the flap design for reconstruction; lower left: flap in place; right: follow-up at 6 months Case II An year-old female patient was sent to our department by her general practitioner for an ulcerated left cheek tumor, with a five-year onset Figure 2. After the clinical and computed tomography examinations Figure 2.
The ophthalmic examination revealed important eyesight impairment. The patient did not have other illnesses. Figure 2. Basal-cell carcinoma of the cheek sintomas de enterobiasis involving the orbit and the nose regions Figure 2.
CT scan showing bony and orbit extension of the tumor The biopsy confirmed the clinical diagnosis: basal-cell carcinoma. A surgical procedure was planned: vierme mare verde surgical excision en bloc with left exenteration and anterior maxillary wall resection, and immediate reconstruction of the soft tissue defect with frontal and advanced cheek flap Figure 2.
A second-stage procedure will be carried on after three weeks for adjusting the frontal flap pedicle. Healing went uneventful Figure 2.
THE MANAGEMENT OF SKIN TUMORS EXTENDED TO THE ORBIT
The patient refused other surgical procedures. Surgical specimen, the defect, and the flap design Figure 2. Immediate postoperative image and after suture removal Discussion There are numerous reports in literature that show an increase in skin cancer incidence, but an exact number cannot be determined because of a variety of factors: not all skin cancer benign vs malignant specimens skin cancer benign vs malignant sent for histological examination, many patients are treated in one-day surgery procedures in private centres that do not usually report all their malignant cases and, last but not least, because skin malignancies are often seen in elderly patients which may not receive adequate treatment due to their health condition.
Topical agents such as fluorouracil or imiquimod have been used for treating skin cancers, but it appears that there is a good prognosis only in premalignant phases and in small basal-cell carcinomas 7.
Но одного физического здоровья, при всей его важности, недоставало для выполнения возникшей задачи. Его тело не обладало нужными навыками. Широкие шаги Хилвара, которыми тот мощно и без видимых усилий преодолевал любой склон, наполняли его завистью и решимостью не сдаваться, пока он в силах передвигать ноги.
Even in these cases, the reports contain small groups of patients, lacking the statistical relevance of large cohorts. It is best suited for a palliative method of treatment in patients who are not good candidates for surgical treatment.
Radiotherapy can enhance the prognosis when dealing with relapse or node involvement, when it is used after the surgical treatment in the multimodal treatment of skin cancers. For patients who refuse surgical resection due to cosmetic reasons, radiotherapy can be used as a primary intention treatment, but the patient should be advised that there is a lower chance of curative intention comparative with surgery.
For late stages of squamous cell carcinomas with lymph node involvement, the most efficient therapy is the surgical treatment resection and neck dissection followed by radiotherapy. When dealing with Skin cancer benign vs malignant stages, neck management must be carefully planned and the cervical nodes should be addressed when there is perineural or perivascular infiltration, poorly differentiated histological types, immunosuppression, more than 2 cm in size or 8 mm depth of the primary tumor Patients who have developed a skin malignancy pose a greater skin cancer benign vs malignant of acquiring a second tumor in time and they are three times more likely to develop a malignant melanoma Specialists recommend to have check-ups twice a year and protection against UV.
Material and methods: We reviewed 18 cases of skin tumors extended to the orbit regarding the initial location, clinical signs, diagnostic methods, the surgical treatment and reconstruction procedure, the tumor histology, as well as the postoperative outcome and complications. Results: The most encountered location of the malignancy was at the level of the inferior eyelid.
The various drug therapies have not yet been proved to play a major role in fighting relapse or metastasis. Conclusions The European population tends to get older and as skin cancers are age-dependent, the clinicians will have to deal in the future with an increasing number of patients.
The vast majority of skin malignancies are found in the head and neck regions, where multiple medical specialists exert their profession, but a better collaboration between professions will ensure a better prognosis for these patients.
Conflict of interests: The authors declare no conflict of interests.