Papillary urothelial carcinoma with squamous differentiation
Medicine Baltimore ; 98 12 : e, Mar.
The identification of sentinel lymph nodes SLNs might improve the postoperative protocols. The aim of this study was to present our experience in detecting SLNs in GC using methylene blue dye.
We have performed an observational study and retrospectively analyzed all of the consecutive cases of GC operated by the same surgical team and managed by the same pathologists during to In all of the cases SLN status was determined using the methylene blue that was intraoperatively administered in the peritumoral subserosal tissue.
All blue colored nodes were histopathologically examined. From the 48 cases, 34 False negativity was observed in 6 of the 14 cases.
In 2 of the cases the false negativity of the group 20 was induced by the anthracotic pigment. In other 2 false negative cases, although no regional metastases were founded, sentinel skip metastases in the group 8 and 15, respectively, were identified.
Papillary urothelial carcinoma with squamous differentiation of the SLNs is a simple and cheap method that might improve the accuracy of LN-based staging of patients with GC and favor identification of skip metastases.